I've potentially got a great system, but the low level crackle that I'm getting is driving me mad

My system:
Scope Profesional
Scope 14 DSP booster
Scope Project
SW1000XG (which I need to keep for the VL board and my WX5, though using it to drive the minimax is lots of fun

Noah EX
P4P800 (basic)
NVidea FX5200 running dual monitor
P4 2.6Ghz
1Gb ram
1 x 120Gb SATA
1 x 80Gb PATA
Windows XP
ACPI enabled
HT enabled
I'm using a seperate hardware profile for my music kit with as many services as possible disabled. All the usual Xp tweaks, no screen saver, remote desktop, indexing turned off, optimised for background services. I was having random lockups, but so far so good. But now I've noticed the crackle, which is low level and quite a harsh digital sound but definitely there, and especially noticable when I use scope synths. It's not that noticable with audio from cubase SX surprisingly.
I've been through a long (and painful)process to get where I am now,ie hopeful stable (but not enough testing time to say for definite) which has resulted in re-arranging the cards so that they have their own interupts, sorting out midi over usb on the noah and using midiox to remove active sensing midi messages, latest bios update (don't like motherboard turning into a brick if the power fails), setting affinity for cubase and SFP4 to seperate CPU's.
From what I've read on planetz I should be able to leave ACPI and HT enabled. Two of the scope cards share an interrupt whilst the other is on a seperate interrupt as is the SW1000XG.
I think I've changed the cset.ini file to reflect the scope professional card as first. But in the routing window the Scope board with I/O is listed second from the top and the DSP load shows 1..14,1..14,1..6.
Could this be the problem?
ACPI? I was under the impression that ACPI and APIC on this board was a combo that worked?
Does HT make that big a difference?
I've also used a tool called Double Dawg to alter latency levels for al the cards including the FX5200. The FX5200 was set at a whopping 248, but altering it didn't help, thought it might be worth pursuing in more depth. I suspected a shared irq for USB and a scope card was the culprit but ditching that USB port didn't help.
Any help for a desperate man from you guru's out there would be greatly appreciated.
tia
Rob
